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 Symposium

Dr John Maher

frame

Dr John Maher leads the "CAR Mechanics" group within King's College London, which is focused on the development of adoptive immunotherapy using CAR and gamma delta T-cells. He played a key role in the early development of second generation CAR technology and is chief investigator of a Phase 1 CAR T-cell clinical trial in head and neck cancer. He is also a consultant immunologist within King's Health Partners and Eastbourne Hospital.

Abstract

The CAR mechanics group has a focus on the development of next generation CAR T-cell technologies that may find application in solid tumours, which heretofore have proven resistant to treatment using this approach. This presentation will span the bench to bedsite development of CAR T-cell immunotherapy, focussing on two target families that are widely expressed in pancreatic and other solid tumour types.